Prospective Phase II Study of Stereotactic Body Proton Therapy for Treatment of PrimAry Renal Cell Carcinoma (SPARE)
Status: Recruiting
Location: See location...
Intervention Type: Radiation
Study Type: Interventional
Study Phase: Phase 2
SUMMARY
This study examines the impact of proton based stereotactic radiation therapy (SBRT) on kidney function as well as other oncologic outcomes including local control, locoregional and systemic failure, progression free and overall survival.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age ≥ 18 years
• Biopsy proven renal cell carcinoma.
• No clinical or radiographic evidence of metastatic disease.
• Not a candidate for surgical treatment or local ablative procedures.
• Subjects are able to undergo either an MRI or administration of contrast agent for CT.
Locations
United States
Washington, D.c.
Sibley Memorial Hospital
RECRUITING
Washington D.c.
Contact Information
Primary
Sherif Shaaban
sshaaba1@jhmi.edu
202-919-2523
Backup
Ryan Manuel
rmanuel5@jhmi.edu
410-955-4261
Time Frame
Start Date: 2025-02-25
Estimated Completion Date: 2030-08
Participants
Target number of participants: 20
Treatments
Experimental: Proton Stereotactic Body Radiation Therapy (SBRT)
The SBRT group is the single arm of this study.
Related Therapeutic Areas
Sponsors
Collaborators: Robert L. Sloan Fund for Cancer Research
Leads: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins